Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04695.1KEGG: ate:Athe_1341 hypothetical protein. (350 aa)    
Predicted Functional Partners:
ADQ04664.1
PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; KEGG: ate:Athe_1310 thiamin pyrophosphokinase catalytic region.
 
     0.837
ADQ04666.1
PFAM: glycosyl transferase family 2; KEGG: ate:Athe_1312 glycosyl transferase family 2.
 
     0.824
ADQ04696.1
PFAM: NUDIX hydrolase; KEGG: ate:Athe_1342 NUDIX hydrolase.
       0.821
ADQ04697.1
KEGG: ate:Athe_1343 PHP domain protein.
       0.820
ADQ04667.1
Hypothetical protein; Manually curated; KEGG: ate:Athe_1313 hypothetical protein.
 
     0.818
ADQ04665.1
KEGG: ate:Athe_1311 hypothetical protein.
 
     0.795
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.779
ADQ04698.1
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.769
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
 
     0.759
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.755
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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