Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04707.1Transcriptional repressor, CopY family; PFAM: Penicillinase repressor; KEGG: ate:Athe_1354 transcriptional repressor, CopY family. (126 aa)    
Predicted Functional Partners:
ADQ04708.1
PFAM: peptidase M56 BlaR1; KEGG: ate:Athe_1355 peptidase M56 BlaR1.
 
 
 0.997
ADQ05501.1
KEGG: ate:Athe_2280 heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; copper ion binding protein; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase.
  
  
 0.828
ADQ05500.1
KEGG: ate:Athe_2279 copper ion binding protein; TIGRFAM: copper ion binding protein; PFAM: Heavy metal transport/detoxification protein.
  
  
 0.593
ADQ04710.1
KEGG: ate:Athe_1357 hypothetical protein.
  
  
 0.585
ADQ04709.1
KEGG: csc:Csac_1917 hypothetical protein.
       0.492
ADQ05592.1
KEGG: ate:Athe_2352 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
 
    0.451
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.444
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
      
 0.426
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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