Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04802.1KEGG: ate:Athe_1465 CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type. (330 aa)    
Predicted Functional Partners:
ADQ04119.1
KEGG: ate:Athe_0660 hypothetical protein.
     0.977
ADQ04803.1
KEGG: ate:Athe_1466 hypothetical protein.
   
 0.952
ADQ04804.1
KEGG: ate:Athe_1467 hypothetical protein.
 
     0.948
ADQ04120.1
KEGG: ate:Athe_0661 hypothetical protein.
   
 0.939
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.535
ADQ04806.1
PFAM: GCN5-related N-acetyltransferase; KEGG: ate:Athe_1469 GCN5-related N-acetyltransferase.
 
     0.487
ADQ04801.1
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ate:Athe_1464 UBA/ThiF-type NAD/FAD binding protein.
       0.400
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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