Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04851.1PFAM: nitroreductase; KEGG: ate:Athe_1518 nitroreductase. (170 aa)    
Predicted Functional Partners:
ADQ05693.1
PFAM: ABC-2 type transporter; KEGG: ate:Athe_2625 ABC-2 type transporter.
 
  
 0.891
ADQ04211.1
PFAM: AMP-dependent synthetase and ligase; KEGG: ate:Athe_0789 AMP-dependent synthetase and ligase.
   
 
 0.822
ADQ04852.1
KEGG: ate:Athe_1519 peptidase S16, lon-like protein.
 
     0.761
ADQ04850.1
PFAM: protein of unknown function UPF0047; KEGG: ate:Athe_1517 protein of unknown function UPF0047.
  
    0.733
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.703
ADQ05692.1
PFAM: ABC-2 type transporter; KEGG: csc:Csac_0514 ABC-2 type transporter.
  
  
 0.695
ADQ04010.1
PFAM: GTP cyclohydrolase II; 34-dihydroxy-2-butanone 4-phosphate synthase; KEGG: ate:Athe_0562 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family.
  
 
 0.628
ADQ05638.1
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ate:Athe_2395 CMP/dCMP deaminase zinc-binding.
  
  
 0.574
ADQ03822.1
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase.
  
  
 0.566
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.490
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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