Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ04910.1KEGG: ate:Athe_1614 hypothetical protein. (124 aa)    
Predicted Functional Partners:
ADQ04909.1
PFAM: Circadian clock protein KaiC central region; KEGG: ate:Athe_1613 putative circadian clock protein, KaiC.
 
   
 0.936
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.554
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
 
     0.536
ADQ03677.1
KEGG: CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57.
  
     0.474
ADQ05466.1
KEGG: ate:Athe_2260 hypothetical protein.
  
     0.471
ADQ05212.1
PFAM: Fibronectin type III domain protein; KEGG: ate:Athe_1944 fibronectin type III domain protein.
  
     0.456
ADQ03645.1
KEGG: csc:Csac_2571 hypothetical protein.
  
     0.432
ADQ05723.1
KEGG: ate:Athe_2712 protein of unknown function DUF114.
  
     0.426
ADQ05582.1
PFAM: S-layer domain-containing protein; KEGG: ate:Athe_2342 S-layer domain protein.
  
     0.424
ADQ03925.1
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
  
     0.411
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.