Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05002.1KEGG: ate:Athe_1713 FeS cluster assembly scaffold protein NifU; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein. (127 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 0.999
ADQ04882.1
PFAM: aminotransferase class V; KEGG: ate:Athe_1547 aminotransferase class V.
 
 0.994
ADQ05680.1
KEGG: ate:Athe_2608 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.949
ADQ05681.1
PFAM: SufBD protein; KEGG: ate:Athe_2609 SufBD protein.
  
  
 0.941
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.914
ADQ05004.1
KEGG: ate:Athe_1715 transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.
 
  
 0.891
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.839
ADQ03633.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.607
ADQ05381.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
   
  
 0.522
ADQ04100.1
TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: ate:Athe_0641 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
   0.484
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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