Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05128.1KEGG: ate:Athe_1838 phage SPO1 DNA polymerase-related protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily. (185 aa)    
Predicted Functional Partners:
argD
TIGRFAM: acetylornithine and succinylornithine aminotransferase; KEGG: ate:Athe_1837 acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
       0.790
ADQ05126.1
PFAM: SNARE associated Golgi protein; KEGG: ate:Athe_1836 SNARE associated Golgi protein.
  
    0.632
ADQ03879.1
PFAM: peptidase M22 glycoprotease; KEGG: ate:Athe_0445 peptidase M22 glycoprotease.
  
    0.572
ADQ05394.1
Flagellar basal-body rod protein FlgC; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
    
   0.504
ADQ04673.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: ate:Athe_1319 conserved carboxylase region.
  
    0.502
ADQ05521.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: csc:Csac_2485 hypothetical protein.
  
    0.502
ADQ04797.1
PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: ate:Athe_1460 single-strand binding protein/primosomal replication protein N.
   
 
 0.496
ADQ05316.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.496
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.487
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
    0.443
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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