Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05130.1KEGG: csc:Csac_2382 GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. (389 aa)    
Predicted Functional Partners:
ADQ05131.1
KEGG: csc:Csac_2383 beta-lactamase superfamily hydrolase.
 
     0.852
ADQ05132.1
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: csc:Csac_2384 diguanylate cyclase; SMART: GGDEF domain containing protein; GAF domain protein.
 
   
0.763
ADQ05134.1
KEGG: ate:Athe_1844 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide TPR_1 repeat-containing protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide repeat.
 
  
 0.750
ADQ03645.1
KEGG: csc:Csac_2571 hypothetical protein.
  
     0.749
ADQ05129.1
PFAM: S-layer domain-containing protein; KEGG: ate:Athe_1839 S-layer domain protein.
 
     0.746
ADQ04027.1
PFAM: PBS lyase HEAT domain protein repeat-containing protein; KEGG: ate:Athe_0578 PBS lyase heat domain protein repeat-containing protein.
 
     0.744
ADQ05582.1
PFAM: S-layer domain-containing protein; KEGG: ate:Athe_2342 S-layer domain protein.
  
     0.738
ADQ05212.1
PFAM: Fibronectin type III domain protein; KEGG: ate:Athe_1944 fibronectin type III domain protein.
  
     0.735
ADQ03873.1
PFAM: S-layer domain-containing protein; KEGG: ate:Athe_0438 S-layer domain protein.
  
     0.733
ADQ04160.1
KEGG: ate:Athe_0715 hypothetical protein.
  
     0.705
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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