Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05172.1KEGG: ate:Athe_1910 transcriptional regulator, GntR family with aminotransferase domain; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH. (462 aa)    
Predicted Functional Partners:
ADQ05173.1
TIGRFAM: amidohydrolase; KEGG: ate:Athe_1911 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein.
 
     0.814
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
  
  
 0.676
pdxT
SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
  
  
 0.657
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
      0.541
ADQ04915.1
PFAM: protein of unknown function DUF34; KEGG: ate:Athe_1619 protein of unknown function DUF34; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
   
    0.525
ADQ05310.1
KEGG: ate:Athe_2085 dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase.
    
 
 0.493
ADQ04548.1
KEGG: ate:Athe_1172 4Fe-4S ferredoxin iron-sulfur binding domain protein.
    
   0.483
ADQ05049.1
KEGG: csc:Csac_2306 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
    
   0.483
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.