STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (314 aa)    
Predicted Functional Partners:
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
  
 0.991
ADQ04997.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: ate:Athe_1708 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.976
ADQ04145.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain-containing protein; KEGG: ate:Athe_0704 transketolase central region.
  
 0.958
ADQ04998.1
KEGG: ate:Athe_1709 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 0.958
ADQ04447.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ate:Athe_1062 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
  
 0.957
ADQ04288.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ate:Athe_0876 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.949
ADQ04481.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ate:Athe_1096 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.949
ADQ04509.1
PFAM: aminotransferase class I and II; KEGG: ate:Athe_1128 aminotransferase class I and II.
  
 0.942
ADQ04745.1
TIGRFAM: pyruvate, phosphate dikinase; KEGG: ate:Athe_1409 pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family.
  
 
 0.935
ADQ04289.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: csc:Csac_1461 thiamine pyrophosphate binding domain-containing protein.
  
 
 0.926
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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