Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05216.1Radical SAM domain protein; KEGG: ate:Athe_1948 coproporphyrinogen dehydrogenase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (471 aa)    
Predicted Functional Partners:
ADQ05215.1
PFAM: Radical SAM domain protein; KEGG: ate:Athe_1947 radical SAM domain protein.
       0.740
argS
TIGRFAM: arginyl-tRNA synthetase; KEGG: ate:Athe_2036 arginyl-tRNA synthetase.
   
    0.678
ADQ05214.1
TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: ate:Athe_1946 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase.
  
  
 0.670
ADQ05217.1
KEGG: ate:Athe_1949 beta-lactamase domain protein.
     
 0.634
ADQ05260.1
PFAM: Domain of unknown function DUF1934; KEGG: ate:Athe_2037 domain of unknown function DUF1934.
  
    0.602
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.561
ADQ05219.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
       0.561
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.558
ADQ05212.1
PFAM: Fibronectin type III domain protein; KEGG: ate:Athe_1944 fibronectin type III domain protein.
 
     0.519
ADQ05213.1
KEGG: ate:Athe_1945 fibronectin type III domain protein; PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein.
       0.471
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.