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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa)    
Predicted Functional Partners:
ADQ04113.1
TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
 
 0.999
ADQ05228.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase.
 
 0.998
ADQ03822.1
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase.
  
 
 0.909
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
     
 0.909
purM
TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: ate:Athe_1447 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
    
 0.904
ADQ05230.1
KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.
  
 
 0.870
ADQ05461.1
TIGRFAM: serine O-acetyltransferase; KEGG: ate:Athe_2254 serine O-acetyltransferase.
     
 0.854
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.833
ADQ05651.1
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.817
ADQ04505.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: ate:Athe_1124 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
    
  0.815
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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