| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADQ03968.1 | alr | Calow_0382 | Calow_1619 | PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Mur ligase middle domain protein; KEGG: ate:Athe_0527 Mur ligase middle domain protein. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.627 |
| ADQ03968.1 | murD | Calow_0382 | Calow_0621 | PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Mur ligase middle domain protein; KEGG: ate:Athe_0527 Mur ligase middle domain protein. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.986 |
| ADQ03968.1 | murI | Calow_0382 | Calow_1723 | PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Mur ligase middle domain protein; KEGG: ate:Athe_0527 Mur ligase middle domain protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.627 |
| ADQ04102.1 | ADQ04103.1 | Calow_0519 | Calow_0520 | TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. | KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.948 |
| ADQ04102.1 | alr | Calow_0519 | Calow_1619 | TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.852 |
| ADQ04102.1 | murI | Calow_0519 | Calow_1723 | TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.881 |
| ADQ04102.1 | purQ | Calow_0519 | Calow_1229 | TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.908 |
| ADQ04103.1 | ADQ04102.1 | Calow_0520 | Calow_0519 | KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. | 0.948 |
| ADQ04103.1 | alr | Calow_0520 | Calow_1619 | KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.800 |
| ADQ04103.1 | murI | Calow_0520 | Calow_1723 | KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.803 |
| ADQ04103.1 | purQ | Calow_0520 | Calow_1229 | KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.901 |
| ADQ04261.1 | murI | Calow_0685 | Calow_1723 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.919 |
| ADQ05260.1 | argS | Calow_1722 | Calow_1721 | PFAM: Domain of unknown function DUF1934; KEGG: ate:Athe_2037 domain of unknown function DUF1934. | TIGRFAM: arginyl-tRNA synthetase; KEGG: ate:Athe_2036 arginyl-tRNA synthetase. | 0.951 |
| ADQ05260.1 | ddl | Calow_1722 | Calow_1724 | PFAM: Domain of unknown function DUF1934; KEGG: ate:Athe_2037 domain of unknown function DUF1934. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.819 |
| ADQ05260.1 | murI | Calow_1722 | Calow_1723 | PFAM: Domain of unknown function DUF1934; KEGG: ate:Athe_2037 domain of unknown function DUF1934. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.778 |
| alr | ADQ03968.1 | Calow_1619 | Calow_0382 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Mur ligase middle domain protein; KEGG: ate:Athe_0527 Mur ligase middle domain protein. | 0.627 |
| alr | ADQ04102.1 | Calow_1619 | Calow_0519 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. | 0.852 |
| alr | ADQ04103.1 | Calow_1619 | Calow_0520 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.800 |
| alr | ddl | Calow_1619 | Calow_1724 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.965 |
| alr | murD | Calow_1619 | Calow_0621 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.644 |