Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05288.1KEGG: ate:Athe_2068 ammonium transporter; TIGRFAM: ammonium transporter; PFAM: ammonium transporter. (406 aa)    
Predicted Functional Partners:
ADQ05287.1
PFAM: nitrogen regulatory protein P-II; KEGG: ate:Athe_2067 nitrogen regulatory protein P-II.
 
 
 0.998
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.634
ADQ04102.1
TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
  
 0.611
ADQ03931.1
PFAM: fumarate lyase; Fumarase C-like; KEGG: ate:Athe_0474 fumarate lyase.
   
  
 0.557
ADQ05449.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: ate:Athe_2238 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
 
    
 0.554
ADQ03965.1
KEGG: ate:Athe_0524 aconitate hydratase; TIGRFAM: aconitate hydratase; homoaconitate hydratase family protein; PFAM: aconitate hydratase domain-containing protein.
  
  
 0.528
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.520
ADQ05740.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-3 domain protein; KEGG: ate:Athe_2740 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein.
     
 0.461
rpsI
PFAM: ribosomal protein S9; KEGG: ate:Athe_2069 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
     
 0.455
ADQ04017.1
PFAM: ANTAR domain protein; KEGG: ate:Athe_0569 response regulator receiver and ANTAR domain protein.
  
  
 0.436
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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