Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05295.1PFAM: Carboxylesterase type B; KEGG: pjd:Pjdr2_4273 carboxylesterase; Belongs to the type-B carboxylesterase/lipase family. (504 aa)    
Predicted Functional Partners:
ADQ05294.1
PFAM: beta-lactamase; KEGG: pjd:Pjdr2_4521 beta-lactamase.
 
     0.811
ADQ05297.1
Ricin B lectin; KEGG: putative esterase; PFAM: Ricin B lectin; esterase; SMART: Ricin B lectin.
 
     0.719
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
  0.711
ADQ04547.1
Transcriptional regulator, Crp/Fnr family; KEGG: ate:Athe_1171 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
   
 
 0.632
ADQ03729.1
Glycoside hydrolase family 43; KEGG: csc:Csac_2411 carbohydrate-binding family 6 protein; PFAM: glycoside hydrolase family 43; Carbohydrate-binding CenC domain protein; Carbohydrate binding family 6; SMART: cellulose binding type IV.
 
     0.629
ADQ04521.1
PFAM: SMC domain protein; KEGG: ate:Athe_1142 SMC domain protein.
    
   0.591
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.536
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
   0.533
ADQ04143.1
PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: ate:Athe_0702 catalytic domain of components of various dehydrogenase complexes.
   
   0.523
ADQ05293.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: bsu:BSU06150 glucitol (sorbitol) dehydrogenase.
     
 0.490
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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