Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05326.1KEGG: ate:Athe_2106 protein of unknown function DUF362. (360 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.731
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
       0.682
ADQ05329.1
KEGG: ate:Athe_2109 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain.
 
     0.676
ADQ05632.1
PFAM: Xylose isomerase domain-containing protein TIM barrel; KEGG: ate:Athe_2389 xylose isomerase domain protein TIM barrel.
  
     0.535
ADQ04946.1
PFAM: Protein of unknown function DUF2442; KEGG: ate:Athe_1650 hypothetical protein.
  
     0.504
ADQ05607.1
KEGG: ate:Athe_2369 hypothetical protein.
  
     0.440
ADQ03826.1
PFAM: major facilitator superfamily MFS_1; KEGG: ate:Athe_0342 major facilitator superfamily MFS_1.
  
     0.439
hpf
Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
       0.420
ADQ05330.1
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
       0.417
ADQ04939.1
PFAM: DNA polymerase beta domain protein region; KEGG: ate:Athe_1643 DNA polymerase beta domain protein region.
  
     0.404
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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