Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05361.1KEGG: ate:Athe_2142 hypothetical protein. (87 aa)    
Predicted Functional Partners:
ADQ05360.1
KEGG: ate:Athe_2141 hypothetical protein.
       0.705
ADQ05362.1
KEGG: ate:Athe_2143 protein of unknown function DUF342; manually curated; PFAM: protein of unknown function DUF342.
       0.631
ADQ05363.1
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.556
ADQ05359.1
KEGG: ate:Athe_2140 hypothetical protein.
       0.547
ADQ05358.1
KEGG: ate:Athe_2139 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain.
       0.516
ADQ05364.1
KEGG: ate:Athe_2145 hypothetical protein.
       0.500
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.488
ADQ05366.1
PFAM: CheC domain protein; KEGG: ate:Athe_2147 CheC, inhibitor of MCP methylation.
       0.488
ADQ05367.1
KEGG: ate:Athe_2148 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
       0.472
ADQ05368.1
KEGG: ate:Athe_2149 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein.
       0.410
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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