Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05409.1TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; KEGG: ate:Athe_2193 Mg chelatase, subunit ChlI; SMART: AAA ATPase. (510 aa)    
Predicted Functional Partners:
ADQ05401.1
KEGG: ate:Athe_2182 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein.
 
 0.845
ADQ04967.1
PFAM: phosphoribosyltransferase; KEGG: ate:Athe_1679 phosphoribosyltransferase.
 
  
 0.795
ADQ04331.1
PFAM: Uncharacterised protein family UPF0102; KEGG: ate:Athe_0977 protein of unknown function UPF0102; Belongs to the UPF0102 family.
 
  
 0.791
ADQ05183.1
KEGG: ate:Athe_1921 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
 
  
 0.698
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.464
ADQ05577.1
KEGG: ate:Athe_2337 flagellar basal-body rod protein FlgG; TIGRFAM: flagellar basal-body rod protein FlgG; fagellar hook-basal body protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein.
   
   0.439
ADQ05578.1
KEGG: ate:Athe_2338 flagellar basal body rod protein; TIGRFAM: fagellar hook-basal body protein; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein.
   
   0.439
ADQ05740.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-3 domain protein; KEGG: ate:Athe_2740 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein.
  
  
 0.430
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.427
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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