Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05435.1KEGG: ate:Athe_2219 4Fe-4S ferredoxin iron-sulfur binding domain protein. (373 aa)    
Predicted Functional Partners:
ADQ04653.1
KEGG: ate:Athe_1299 hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit.
  
 
 0.965
ADQ04649.1
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: ate:Athe_1295 NADH dehydrogenase (ubiquinone) 24 kDa subunit.
  
 
 0.823
ADQ04646.1
PFAM: Fe-S cluster domain protein; KEGG: ate:Athe_1292 Fe-S cluster domain protein.
   
 
 0.690
ADQ05434.1
KEGG: ate:Athe_2218 glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.
       0.468
ADQ05433.1
KEGG: ate:Athe_2217 anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein.
       0.451
ADQ03923.1
PFAM: aldo/keto reductase; KEGG: ate:Athe_0465 aldo/keto reductase.
 
    0.445
ADQ05432.1
PFAM: aminotransferase class IV; KEGG: ate:Athe_2216 aminotransferase class IV.
       0.433
ADQ05354.1
KEGG: ate:Athe_2135 protein of unknown function DUF362.
 
     0.428
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
    0.423
ADQ05318.1
PFAM: aldo/keto reductase; KEGG: csc:Csac_1334 aldo/keto reductase.
 
    0.417
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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