Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05437.1PFAM: pyruvate carboxyltransferase; KEGG: csc:Csac_0724 pyruvate carboxyltransferase. (452 aa)    
Predicted Functional Partners:
ADQ04997.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: ate:Athe_1708 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.912
ADQ04998.1
KEGG: ate:Athe_1709 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.912
ADQ04143.1
PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: ate:Athe_0702 catalytic domain of components of various dehydrogenase complexes.
    
 0.910
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.903
ADQ04288.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ate:Athe_0876 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
   
 
 0.903
ADQ04289.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: csc:Csac_1461 thiamine pyrophosphate binding domain-containing protein.
   
 
 0.903
ADQ04481.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ate:Athe_1096 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
   
 
 0.903
ADQ04482.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: ate:Athe_1097 thiamine pyrophosphate protein domain protein TPP-binding.
   
 
 0.903
ADQ04286.1
KEGG: ate:Athe_0874 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
    
 0.902
ADQ03961.1
PFAM: pyruvate carboxyltransferase; KEGG: ate:Athe_0518 pyruvate carboxyltransferase.
  
  
 
0.901
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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