Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05439.1Transcriptional regulator, GntR family with LacI sensor; KEGG: csc:Csac_0722 regulatory protein GntR, HTH; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH. (374 aa)    
Predicted Functional Partners:
ADQ05438.1
PFAM: class II aldolase/adducin family protein; KEGG: csc:Csac_0723 L-ribulose-5-phosphate 4-epimerase.
 
  
 0.849
ADQ05296.1
KEGG: cce:Ccel_3464 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
  
     0.734
araB
L-ribulokinase; KEGG: ate:Athe_2229 L-ribulokinase; TIGRFAM: L-ribulokinase; PFAM: Carbohydrate kinase, FGGY-like.
 
   
 0.648
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
    
 
 0.534
ADQ04145.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain-containing protein; KEGG: ate:Athe_0704 transketolase central region.
    
 
 0.528
ADQ03696.1
Phosphotransferase system, phosphocarrier protein HPr; KEGG: ate:Athe_0150 phosphocarrier, HPr family; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
   
 
 0.514
ADQ03820.1
Phosphotransferase system, phosphocarrier protein HPr; KEGG: ate:Athe_0323 phosphocarrier, HPr family; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
   
 
 0.514
ADQ04635.1
KEGG: ate:Athe_1281 hypothetical protein.
   
 
 0.507
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.499
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
   0.484
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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