STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05513.1PFAM: protein of unknown function DUF214; KEGG: csc:Csac_2446 hypothetical protein. (332 aa)    
Predicted Functional Partners:
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.999
ADQ05683.1
KEGG: ate:Athe_2611 efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.988
ADQ04903.1
KEGG: ate:Athe_1583 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.985
ADQ05407.1
KEGG: ate:Athe_2191 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    0.875
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
    
 0.843
ADQ05208.1
KEGG: ate:Athe_1940 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
      0.755
ADQ04902.1
PFAM: protein of unknown function DUF214; KEGG: ate:Athe_1582 protein of unknown function DUF214.
  
  
 0.632
ADQ05512.1
KEGG: ate:Athe_2295 S-layer domain protein.
     
 0.592
ADQ04108.1
KEGG: ate:Athe_0649 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein.
   
    0.489
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.444
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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