Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05513.1PFAM: protein of unknown function DUF214; KEGG: csc:Csac_2446 hypothetical protein. (332 aa)    
Predicted Functional Partners:
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.999
ADQ05683.1
KEGG: ate:Athe_2611 efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.985
ADQ04903.1
KEGG: ate:Athe_1583 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.976
ADQ05407.1
KEGG: ate:Athe_2191 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    0.874
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
    
 0.846
ADQ05208.1
KEGG: ate:Athe_1940 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
      0.755
ADQ05512.1
KEGG: ate:Athe_2295 S-layer domain protein.
     
 0.568
ADQ04108.1
KEGG: ate:Athe_0649 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein.
   
    0.535
ADQ04902.1
PFAM: protein of unknown function DUF214; KEGG: ate:Athe_1582 protein of unknown function DUF214.
  
  
 0.534
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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