Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
macBABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (241 aa)    
Predicted Functional Partners:
ADQ05513.1
PFAM: protein of unknown function DUF214; KEGG: csc:Csac_2446 hypothetical protein.
 
 0.999
ADQ05682.1
PFAM: protein of unknown function DUF214; KEGG: csc:Csac_0529 hypothetical protein.
 
 0.996
ADQ04902.1
PFAM: protein of unknown function DUF214; KEGG: ate:Athe_1582 protein of unknown function DUF214.
  
 
 0.976
ADQ05683.1
KEGG: ate:Athe_2611 efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.964
ADQ05512.1
KEGG: ate:Athe_2295 S-layer domain protein.
     
 0.578
ADQ05209.1
KEGG: ate:Athe_1941 polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component.
 
 
  
 0.474
ADQ04792.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ate:Athe_1455 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
  
 
 0.464
ADQ05039.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ate:Athe_1750 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
  
 
 0.464
ADQ05670.1
KEGG: ate:Athe_2589 histidine kinase.
  
 
 0.464
ADQ04650.1
KEGG: ate:Athe_1296 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
 
 0.448
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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