STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05558.1KEGG: site-specific DNA-methyltransferase (adenine-specific); PFAM: N-6 DNA methylase. (514 aa)    
Predicted Functional Partners:
ADQ05557.1
PFAM: restriction modification system DNA specificity domain; KEGG: gyc:GYMC61_0287 restriction modification system DNA specificity domain protein.
 
 
 0.999
ADQ05556.1
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.998
ADQ05555.1
PFAM: SMC domain protein; KEGG: tit:Thit_1894 SMC domain protein.
  
  
 0.785
ADQ05559.1
KEGG: hypothetical protein.
       0.705
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.670
ADQ04950.1
PFAM: flagellar protein FlaG protein; KEGG: csc:Csac_1698 flagellar protein FlaG protein.
    
   0.644
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.560
ADQ05113.1
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: ate:Athe_1823 fibronectin-binding A domain protein.
  
    0.515
ADQ04375.1
PFAM: restriction endonuclease; KEGG: cph:Cpha266_1614 restriction endonuclease.
  
  
 0.444
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
   0.428
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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