Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05596.1PFAM: glutamate synthase alpha subunit domain protein; KEGG: ate:Athe_2357 glutamate synthase alpha subunit domain protein. (250 aa)    
Predicted Functional Partners:
ADQ05600.1
PFAM: glutamine amidotransferase class-II; KEGG: ate:Athe_2361 glutamine amidotransferase class-II.
   0.998
ADQ04103.1
KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.987
ADQ05599.1
KEGG: ate:Athe_2360 glutamate synthase (NADPH); PFAM: ferredoxin-dependent glutamate synthase.
 
 0.980
ADQ05597.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ate:Athe_2358 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
  
 0.932
ADQ05598.1
KEGG: ate:Athe_2359 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
     0.881
hisI
KEGG: ate:Athe_1472 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family.
     
 0.504
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.490
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
  
  
 0.481
pheT
KEGG: ate:Athe_1284 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
     
 0.466
ADQ04010.1
PFAM: GTP cyclohydrolase II; 34-dihydroxy-2-butanone 4-phosphate synthase; KEGG: ate:Athe_0562 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family.
     
 0.447
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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