Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05625.1KEGG: ate:Athe_2382 protein of unknown function DUF1121. (212 aa)    
Predicted Functional Partners:
ADQ05626.1
KEGG: csc:Csac_2718 2-deoxy-D-gluconate 3-dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR.
   
   0.719
kduI
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
       0.626
ADQ05630.1
KEGG: csc:Csac_0352 regulatory protein, IclR; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR.
       0.571
ADQ05628.1
PFAM: PfkB domain protein; KEGG: csc:Csac_2720 ribokinase-like domain-containing protein.
       0.554
ADQ05629.1
KEGG: csc:Csac_0354 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
       0.554
ADQ04104.1
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; KEGG: ate:Athe_0645 oxidoreductase FAD/NAD(P)-binding domain protein.
  
   0.450
pyrK
Oxidoreductase FAD/NAD(P)-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
   0.450
ADQ05624.1
PFAM: glycosyl hydrolase family 88; KEGG: csc:Csac_0360 glycosy hydrolase family protein.
  
    0.447
ADQ03923.1
PFAM: aldo/keto reductase; KEGG: ate:Athe_0465 aldo/keto reductase.
   
   0.435
ADQ04564.1
PFAM: aldo/keto reductase; KEGG: ate:Athe_1210 aldo/keto reductase.
   
   0.435
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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