Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ADQ05626.1KEGG: csc:Csac_2718 2-deoxy-D-gluconate 3-dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR. (253 aa)    
Predicted Functional Partners:
kduI
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
 
 0.991
ADQ05628.1
PFAM: PfkB domain protein; KEGG: csc:Csac_2720 ribokinase-like domain-containing protein.
   
 0.933
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
  
 
 0.911
ADQ04091.1
TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; KEGG: ate:Athe_0632 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase.
    
 0.816
ADQ04431.1
TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: ate:Athe_1047 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase.
   
 
 0.813
ADQ05625.1
KEGG: ate:Athe_2382 protein of unknown function DUF1121.
   
   0.719
ADQ05629.1
KEGG: csc:Csac_0354 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
 
  
 0.694
ADQ05630.1
KEGG: csc:Csac_0352 regulatory protein, IclR; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR.
 
   
 0.683
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.612
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.606
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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