Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADQ05631.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: ate:Athe_2388 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding. (323 aa)    
Predicted Functional Partners:
ADQ05629.1
KEGG: csc:Csac_0354 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
    
  0.948
ADQ05291.1
TIGRFAM: glycerate kinase; KEGG: ate:Athe_2071 glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
    
 0.926
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
 
 
 0.812
ADQ05632.1
PFAM: Xylose isomerase domain-containing protein TIM barrel; KEGG: ate:Athe_2389 xylose isomerase domain protein TIM barrel.
 
    0.749
ADQ05740.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-3 domain protein; KEGG: ate:Athe_2740 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein.
     
 0.615
ADQ05633.1
TIGRFAM: ketose-bisphosphate aldolase; KEGG: ate:Athe_2390 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
     
 0.612
xylB-2
PFAM: Carbohydrate kinase, FGGY-like; KEGG: ate:Athe_2391 carbohydrate kinase FGGY.
  
  
 0.573
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.536
ADQ05628.1
PFAM: PfkB domain protein; KEGG: csc:Csac_2720 ribokinase-like domain-containing protein.
  
  
 0.518
ADQ05449.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: ate:Athe_2238 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
     
 0.514
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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