Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
xylB-2PFAM: Carbohydrate kinase, FGGY-like; KEGG: ate:Athe_2391 carbohydrate kinase FGGY. (497 aa)    
Predicted Functional Partners:
xylA
TIGRFAM: xylose isomerase; KEGG: ate:Athe_0603 xylose isomerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; Belongs to the xylose isomerase family.
  
 
 0.961
ADQ04431.1
TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: ate:Athe_1047 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase.
    
 0.943
ADQ05438.1
PFAM: class II aldolase/adducin family protein; KEGG: csc:Csac_0723 L-ribulose-5-phosphate 4-epimerase.
  
 
 0.939
xylB
Xylulokinase; KEGG: ate:Athe_0567 xylulokinase; TIGRFAM: xylulokinase; PFAM: Carbohydrate kinase, FGGY-like.
  
  
 
0.911
ADQ05633.1
TIGRFAM: ketose-bisphosphate aldolase; KEGG: ate:Athe_2390 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
  
  
 0.748
ADQ05632.1
PFAM: Xylose isomerase domain-containing protein TIM barrel; KEGG: ate:Athe_2389 xylose isomerase domain protein TIM barrel.
  
  
 0.675
ADQ05635.1
KEGG: ate:Athe_2392 transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR.
     
 0.644
ADQ05631.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: ate:Athe_2388 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
  
  
 0.573
ADQ03695.1
KEGG: ate:Athe_0149 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system EIIC.
     
 0.463
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.443
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (16%) [HD]