Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05637.1PFAM: ATP-binding region ATPase domain protein; KEGG: ate:Athe_2394 putative anti-sigma regulatory factor, serine/threonine protein kinase. (150 aa)    
Predicted Functional Partners:
ADQ03870.1
KEGG: ate:Athe_0435 anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
 
 
 0.843
ADQ05749.1
TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation protein E; PAS fold-4 domain protein; KEGG: ate:Athe_2749 putative PAS/PAC sensor protein; SMART: protein phosphatase 2C domain protein.
 
 
 0.823
ADQ04004.1
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: tte:TTE1047 STAS domain-containing protein.
  
 
 0.749
ADQ04005.1
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: tte:TTE1048 STAS domain-containing protein.
  
 
 0.749
ADQ04970.1
KEGG: ate:Athe_1682 anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
  
 
 0.749
ADQ05200.1
KEGG: ate:Athe_1018 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein.
 
 
 0.702
ADQ03872.1
KEGG: ate:Athe_0437 RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; TIGRFAM: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein.
 
 
 0.695
ADQ05740.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-3 domain protein; KEGG: ate:Athe_2740 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.672
ADQ04968.1
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.635
ADQ05363.1
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.632
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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