Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05656.1KEGG: csc:Csac_0432 hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family. (372 aa)    
Predicted Functional Partners:
ADQ05657.1
PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: bfs:BF2901 putative uroporphirinogen biosynthesis-related protein.
 
     0.895
ADQ05304.1
KEGG: ate:Athe_2076 glycoside hydrolase family 2 sugar binding.
  
    0.705
ADQ05666.1
PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; KEGG: ate:Athe_2582 methionine synthase.
 
  
 0.689
ADQ05665.1
KEGG: csc:Csac_0424 hypothetical protein.
 
    0.671
ADQ03863.1
PFAM: ferredoxin; KEGG: ate:Athe_0428 ferredoxin.
 
  
 0.625
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.621
ADQ03822.1
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase.
 
  
 0.522
ADQ05575.1
PFAM: Xylose isomerase domain-containing protein TIM barrel; KEGG: csc:Csac_0598 xylose isomerase domain-containing protein.
  
    0.481
ADQ05655.1
KEGG: csc:Csac_0437 hypothetical protein; Belongs to the glycosyl hydrolase 43 family.
       0.475
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.457
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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