STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05657.1PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: bfs:BF2901 putative uroporphirinogen biosynthesis-related protein. (352 aa)    
Predicted Functional Partners:
ADQ04889.1
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
 
 0.915
ADQ05656.1
KEGG: csc:Csac_0432 hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
 
     0.895
ADQ05666.1
PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; KEGG: ate:Athe_2582 methionine synthase.
  
 0.824
ADQ03863.1
PFAM: ferredoxin; KEGG: ate:Athe_0428 ferredoxin.
 
    0.738
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.601
ADQ03822.1
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase.
 
   
 0.546
ADQ05655.1
KEGG: csc:Csac_0437 hypothetical protein; Belongs to the glycosyl hydrolase 43 family.
       0.475
ADQ05658.1
PFAM: extracellular solute-binding protein family 1; KEGG: ate:Athe_2574 extracellular solute-binding protein family 1.
       0.430
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.404
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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