close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05666.1PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; KEGG: ate:Athe_2582 methionine synthase. (213 aa)    
Predicted Functional Partners:
ADQ03822.1
PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase.
  
 0.983
ADQ04172.1
PFAM: dihydropteroate synthase DHPS; KEGG: ate:Athe_0749 dihydropteroate synthase DhpS.
  
 0.981
ADQ03821.1
PFAM: homocysteine S-methyltransferase; KEGG: ate:Athe_0324 homocysteine S-methyltransferase.
  
 0.979
ADQ03863.1
PFAM: ferredoxin; KEGG: ate:Athe_0428 ferredoxin.
 
    0.836
ADQ05657.1
PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: bfs:BF2901 putative uroporphirinogen biosynthesis-related protein.
  
 0.824
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
 
 0.802
ADQ05665.1
KEGG: csc:Csac_0424 hypothetical protein.
 
     0.758
ADQ05656.1
KEGG: csc:Csac_0432 hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 0.706
ADQ05664.1
PFAM: class II aldolase/adducin family protein; KEGG: csc:Csac_0425 class II aldolase/adducin family protein.
  
    0.625
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: medium (48%) [HD]