Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05675.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (491 aa)    
Predicted Functional Partners:
ADQ04347.1
TIGRFAM: stage III sporulation protein AD; KEGG: ate:Athe_0993 hypothetical protein.
  
  
 0.930
ADQ04105.1
KEGG: ate:Athe_0646 hypothetical protein.
  
  
 0.883
ADQ04344.1
SMART: AAA ATPase; KEGG: ate:Athe_0990 AAA ATPase.
  
  
 0.881
ADQ03763.1
KEGG: ate:Athe_0218 stage II sporulation protein D; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation protein D.
  
  
 0.875
ADQ05078.1
KEGG: ate:Athe_1789 stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein.
 
   
 0.863
ADQ04691.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.858
ADQ05222.1
PFAM: Sporulation stage II protein R; KEGG: ate:Athe_1953 hypothetical protein.
  
   
 0.835
ADQ04583.1
KEGG: ate:Athe_1229 nucleoside recognition domain protein.
  
   
 0.833
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.825
ADQ03762.1
Protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; KEGG: ate:Athe_0217 protein serine/threonine phosphatase; SMART: protein phosphatase 2C domain protein.
  
   
 0.823
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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