STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05678.1KEGG: ate:Athe_2606 thioredoxin-disulfide reductase; manually curated; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (292 aa)    
Predicted Functional Partners:
ADQ04921.1
Thioredoxin; KEGG: csc:Csac_1727 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family.
 
 0.989
ADQ03633.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.915
ADQ05160.1
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: ate:Athe_1898 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
  
 
 0.769
ADQ05702.1
TIGRFAM: redox-active disulfide protein 2; KEGG: ate:Athe_2641 redox-active disulfide protein 2.
  
 
 0.748
ADQ04144.1
KEGG: ate:Athe_0703 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.
  
 
 0.667
ADQ03974.1
KEGG: ate:Athe_0533 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein.
 
  
 0.636
ADQ04856.1
KEGG: ate:Athe_1523 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein.
 
  
 0.635
ADQ05679.1
PFAM: protein of unknown function DUF970; KEGG: ate:Athe_2607 protein of unknown function DUF970.
       0.623
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.613
ADQ05680.1
KEGG: ate:Athe_2608 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.584
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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