Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05699.1KEGG: ate:Athe_2627 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR. (213 aa)    
Predicted Functional Partners:
ADQ05740.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-3 domain protein; KEGG: ate:Athe_2740 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.791
ADQ05040.1
KEGG: ate:Athe_1751 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
  
 
 0.747
ADQ04032.1
KEGG: ate:Athe_0583 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
   
 0.725
ADQ05449.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: ate:Athe_2238 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
  
 
 0.697
ADQ05039.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ate:Athe_1750 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 
 0.673
ADQ04792.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ate:Athe_1455 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 
 0.661
ADQ04848.1
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ate:Athe_1511 diguanylate cyclase with GAF sensor; SMART: GGDEF domain containing protein.
  
 
 0.660
ADQ05132.1
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: csc:Csac_2384 diguanylate cyclase; SMART: GGDEF domain containing protein; GAF domain protein.
  
 
 0.660
ADQ05444.1
KEGG: ate:Athe_2233 hypothetical protein.
  
 
 0.658
ADQ05445.1
KEGG: ate:Athe_2234 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
     0.623
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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