Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADQ05725.1PFAM: BioY protein; KEGG: ate:Athe_2725 BioY protein. (184 aa)    
Predicted Functional Partners:
ADQ04973.1
PFAM: cobalt transport protein; KEGG: ate:Athe_1686 cobalt transport protein.
 
 0.960
ecfA
ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.936
ecfA-2
ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.935
ADQ05650.1
PFAM: BioY protein; KEGG: csc:Csac_0304 BioY protein.
  
  
 
0.921
ADQ04282.1
PFAM: cobalt transport protein; KEGG: ate:Athe_0859 cobalt transport protein.
  
 
 0.741
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.729
ADQ04283.1
KEGG: ate:Athe_0860 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
   
 
 0.624
ADQ05724.1
PFAM: Rhomboid family protein; KEGG: ate:Athe_2713 rhomboid family protein.
 
     0.501
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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