Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05731.1KEGG: ate:Athe_2731 stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein. (159 aa)    
Predicted Functional Partners:
ADQ05732.1
KEGG: ate:Athe_2732 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
 
  
 0.986
ADQ05733.1
KEGG: ate:Athe_2733 stage V sporulation protein AE; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein.
 
  
0.880
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.869
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.821
ADQ04087.1
Sporulation protein, YlmC/YmxH family; KEGG: csc:Csac_1196 PRC-barrel domain-containing protein; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain protein.
  
    0.808
ADQ04105.1
KEGG: ate:Athe_0646 hypothetical protein.
  
   
 0.797
ADQ05675.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.797
ADQ04690.1
TIGRFAM: stage IV sporulation protein B; KEGG: ate:Athe_1336 stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB.
  
   
 0.795
ADQ04347.1
TIGRFAM: stage III sporulation protein AD; KEGG: ate:Athe_0993 hypothetical protein.
  
   
 0.792
ADQ05225.1
PFAM: GerA spore germination protein; KEGG: ate:Athe_1956 GerA spore germination protein.
  
  
 0.790
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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