Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ05733.1KEGG: ate:Athe_2733 stage V sporulation protein AE; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein. (117 aa)    
Predicted Functional Partners:
ADQ05732.1
KEGG: ate:Athe_2732 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
 
  
 0.975
ADQ05731.1
KEGG: ate:Athe_2731 stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein.
 
  
0.880
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
     0.814
ADQ04690.1
TIGRFAM: stage IV sporulation protein B; KEGG: ate:Athe_1336 stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB.
  
   
 0.794
ADQ04347.1
TIGRFAM: stage III sporulation protein AD; KEGG: ate:Athe_0993 hypothetical protein.
  
   
 0.793
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.784
ADQ05225.1
PFAM: GerA spore germination protein; KEGG: ate:Athe_1956 GerA spore germination protein.
  
  
 0.784
ADQ05675.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.782
ADQ05764.1
PFAM: GerA spore germination protein; KEGG: ate:Athe_2765 GerA spore germination protein.
  
  
 0.781
ADQ04344.1
SMART: AAA ATPase; KEGG: ate:Athe_0990 AAA ATPase.
  
   
 0.780
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.