Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADQ05751.1TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: ate:Athe_2751 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family. (285 aa)    
Predicted Functional Partners:
ADQ05752.1
KEGG: ate:Athe_2752 cobyrinic acid ac-diamide synthase.
 
 
 0.998
ADQ04334.1
Manually curated; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; KEGG: ate:Athe_0980 cell divisionFtsK/SpoIIIE; SMART: AAA ATPase.
  
  
 0.760
ADQ04479.1
KEGG: ate:Athe_1094 hypothetical protein.
  
 
 0.744
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.735
ADQ05755.1
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: ate:Athe_2755 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
 
   
0.674
ADQ05750.1
KEGG: ate:Athe_2750 hypothetical protein.
  
 
 0.668
rsmG
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.659
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
  
 0.631
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.560
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
   
  
 0.528
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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