Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05752.1KEGG: ate:Athe_2752 cobyrinic acid ac-diamide synthase. (263 aa)    
Predicted Functional Partners:
ADQ05751.1
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: ate:Athe_2751 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
 
 
 0.998
ADQ05755.1
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: ate:Athe_2755 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
 
 
 0.947
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.752
ADQ05750.1
KEGG: ate:Athe_2750 hypothetical protein.
  
  
 0.653
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.644
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
    0.604
ADQ03686.1
KEGG: swo:Swol_1120 hypothetical protein.
  
 
 0.593
ADQ03711.1
PFAM: glycosyl transferase family 2; KEGG: ate:Athe_0167 glycosyl transferase family 2.
  
 
 0.593
ADQ03888.1
PFAM: glycosyl transferase family 2; KEGG: ate:Athe_0452 glycosyl transferase family 2.
  
 
 0.593
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.559
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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