STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROP_15150Hypothetical protein. (206 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.848
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
 0.666
ROP_54440
Hypothetical protein.
 
   
 0.639
ROP_28860
Putative RNA-directed DNA polymerase; Protein synonym:reverse transcriptase.
 
  
 0.589
ROP_45450
Putative RNA-directed DNA polymerase; Protein synonym:reverse transcriptase.
 
  
 0.589
ROP_17520
Hypothetical protein.
  
  
 0.565
ROP_34940
Hypothetical protein.
  
  
 0.565
ROP_15140
Hypothetical protein.
       0.563
ROP_15160
Hypothetical protein.
     
 0.547
ROP_34950
Hypothetical protein.
  
  
 0.478
Your Current Organism:
Rhodococcus opacus
NCBI taxonomy Id: 632772
Other names: R. opacus B4, Rhodococcus opacus B4, Rhodococcus opacus str. B4, Rhodococcus opacus strain B4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.