node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ROP_07140 | ROP_16260 | ROP_07140 | ROP_16260 | Putative 3-isopropylmalate dehydrogenase. | Putative threonine dehydratase; Protein synonym:threonine deaminase. | 0.971 |
ROP_07140 | ROP_37230 | ROP_07140 | ROP_37230 | Putative 3-isopropylmalate dehydrogenase. | Hypothetical protein; Belongs to the TPP enzyme family. | 0.860 |
ROP_07140 | ilvA | ROP_07140 | ROP_07930 | Putative 3-isopropylmalate dehydrogenase. | Protein synonym:threonine deaminase. | 0.971 |
ROP_07140 | ilvC | ROP_07140 | ROP_65410 | Putative 3-isopropylmalate dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.942 |
ROP_07140 | ilvN | ROP_07140 | ROP_65400 | Putative 3-isopropylmalate dehydrogenase. | Acetolactate synthase small subunit; Protein synonym:acetohydroxyacid synthase. | 0.944 |
ROP_07140 | leuB | ROP_07140 | ROP_65430 | Putative 3-isopropylmalate dehydrogenase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.918 |
ROP_07140 | poxB | ROP_07140 | ROP_07940 | Putative 3-isopropylmalate dehydrogenase. | Protein synonym:pyruvate oxidase; Belongs to the TPP enzyme family. | 0.563 |
ROP_16260 | ROP_07140 | ROP_16260 | ROP_07140 | Putative threonine dehydratase; Protein synonym:threonine deaminase. | Putative 3-isopropylmalate dehydrogenase. | 0.971 |
ROP_16260 | ROP_37230 | ROP_16260 | ROP_37230 | Putative threonine dehydratase; Protein synonym:threonine deaminase. | Hypothetical protein; Belongs to the TPP enzyme family. | 0.835 |
ROP_16260 | ilvA | ROP_16260 | ROP_07930 | Putative threonine dehydratase; Protein synonym:threonine deaminase. | Protein synonym:threonine deaminase. | 0.926 |
ROP_16260 | ilvC | ROP_16260 | ROP_65410 | Putative threonine dehydratase; Protein synonym:threonine deaminase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.875 |
ROP_16260 | ilvN | ROP_16260 | ROP_65400 | Putative threonine dehydratase; Protein synonym:threonine deaminase. | Acetolactate synthase small subunit; Protein synonym:acetohydroxyacid synthase. | 0.904 |
ROP_16260 | leuB | ROP_16260 | ROP_65430 | Putative threonine dehydratase; Protein synonym:threonine deaminase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.970 |
ROP_16260 | poxB | ROP_16260 | ROP_07940 | Putative threonine dehydratase; Protein synonym:threonine deaminase. | Protein synonym:pyruvate oxidase; Belongs to the TPP enzyme family. | 0.424 |
ROP_28310 | ROP_37230 | ROP_28310 | ROP_37230 | Putative 4-carboxy-4-hydroxy-2-oxoadipate aldolase. | Hypothetical protein; Belongs to the TPP enzyme family. | 0.920 |
ROP_28310 | ilvN | ROP_28310 | ROP_65400 | Putative 4-carboxy-4-hydroxy-2-oxoadipate aldolase. | Acetolactate synthase small subunit; Protein synonym:acetohydroxyacid synthase. | 0.901 |
ROP_37230 | ROP_07140 | ROP_37230 | ROP_07140 | Hypothetical protein; Belongs to the TPP enzyme family. | Putative 3-isopropylmalate dehydrogenase. | 0.860 |
ROP_37230 | ROP_16260 | ROP_37230 | ROP_16260 | Hypothetical protein; Belongs to the TPP enzyme family. | Putative threonine dehydratase; Protein synonym:threonine deaminase. | 0.835 |
ROP_37230 | ROP_28310 | ROP_37230 | ROP_28310 | Hypothetical protein; Belongs to the TPP enzyme family. | Putative 4-carboxy-4-hydroxy-2-oxoadipate aldolase. | 0.920 |
ROP_37230 | ROP_48970 | ROP_37230 | ROP_48970 | Hypothetical protein; Belongs to the TPP enzyme family. | Tartrate dehydrogenase/tartrate decarboxylase/D-malate dehydrogenase; Multifunctional protein. | 0.959 |