STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabDSuccinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (482 aa)    
Predicted Functional Partners:
gabT-3
4-aminobutyrate aminotransferase; Protein synonym:GABA transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.938
gabT
4-aminobutyrate aminotransferase; Protein synonym:GABA transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.934
gabT-2
4-aminobutyrate aminotransferase; Protein synonym:GABA transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.907
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.906
pyc-2
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.906
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.851
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.846
mqo
Putative malate--quinone oxidoreductase.
  
 
 0.845
icd-2
Isocitrate dehydrogenase; Protein synonym:oxalosuccinate decarboxylase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.841
ROP_59610
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.836
Your Current Organism:
Rhodococcus opacus
NCBI taxonomy Id: 632772
Other names: R. opacus B4, Rhodococcus opacus B4, Rhodococcus opacus str. B4, Rhodococcus opacus strain B4
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