EET48511.1 protein (Thalassobium sp. R2A62) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

EET48511.1

3-oxoacid CoA-transferase, A subunit family; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429. (237 aa)

Predicted Functional Partners:

EET47022.1

0.999

EET49139.1

0.940

EET48020.1

0.940

EET47223.1

0.888

EET46376.1

0.880

EET47917.1

0.879

EET48249.1

0.844

EET46881.1

0.733

EET47014.1

0.733

EET48478.1

0.731

Your Current Organism:

Thalassobium sp. R2A62

NCBI taxonomy Id: 633131
Other names: T. sp. R2A62, Thalassiobium sp. R2A62, alpha proteobacterium R2A62

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EET46376.1	EET47022.1	TR2A62_3627	TR2A62_1871	Conserved hypothetical protein; Identified by match to protein family HMM PF05853.	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	0.867
EET46376.1	EET48511.1	TR2A62_3627	TR2A62_1870	Conserved hypothetical protein; Identified by match to protein family HMM PF05853.	3-oxoacid CoA-transferase, A subunit family; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429.	0.880
EET46881.1	EET47022.1	TR2A62_2175	TR2A62_1871	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	0.740
EET46881.1	EET47917.1	TR2A62_2175	TR2A62_3019	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyryl-coa dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.	0.990
EET46881.1	EET48020.1	TR2A62_2175	TR2A62_3438	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	Fatty acid oxidation complex subunit alpha; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF01210; match to protein family HMM PF02737.	0.999
EET46881.1	EET48511.1	TR2A62_2175	TR2A62_1870	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	3-oxoacid CoA-transferase, A subunit family; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429.	0.733
EET46881.1	EET49139.1	TR2A62_2175	TR2A62_0179	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase NAD-binding; Identified by match to protein family HMM PF00378; match to protein family HMM PF02737; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
EET47014.1	EET47022.1	TR2A62_2722	TR2A62_1871	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	0.740
EET47014.1	EET47917.1	TR2A62_2722	TR2A62_3019	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyryl-coa dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.	0.988
EET47014.1	EET48020.1	TR2A62_2722	TR2A62_3438	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	Fatty acid oxidation complex subunit alpha; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF01210; match to protein family HMM PF02737.	0.999
EET47014.1	EET48511.1	TR2A62_2722	TR2A62_1870	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	3-oxoacid CoA-transferase, A subunit family; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02429.	0.733
EET47014.1	EET49139.1	TR2A62_2722	TR2A62_0179	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase NAD-binding; Identified by match to protein family HMM PF00378; match to protein family HMM PF02737; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
EET47022.1	EET46376.1	TR2A62_1871	TR2A62_3627	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	Conserved hypothetical protein; Identified by match to protein family HMM PF05853.	0.867
EET47022.1	EET46881.1	TR2A62_1871	TR2A62_2175	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	0.740
EET47022.1	EET47014.1	TR2A62_1871	TR2A62_2722	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	0.740
EET47022.1	EET47223.1	TR2A62_1871	TR2A62_2992	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	NAD-dependent 4-hydroxybutyrate dehydrogenase; Identified by match to protein family HMM PF00465.	0.895
EET47022.1	EET47917.1	TR2A62_1871	TR2A62_3019	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	3-hydroxybutyryl-coa dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.	0.884
EET47022.1	EET48020.1	TR2A62_1871	TR2A62_3438	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	Fatty acid oxidation complex subunit alpha; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF01210; match to protein family HMM PF02737.	0.949
EET47022.1	EET48249.1	TR2A62_1871	TR2A62_1213	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	Short-chain dehydrogenase/reductase SDR; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.845
EET47022.1	EET48478.1	TR2A62_1871	TR2A62_3441	Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b; Identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428.	Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.	0.739

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Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

5 of 436

1.16

0.77

0.0101

GO:0016020

Membrane

8 of 2240

0.65

0.43

0.0172

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2429

Mixed, incl. Putative ephrin-receptor like, and GPCR ligand binding

7 of 16

2.74

7.27

7.35e-15

CL:2431

Mixed, incl. Putative ephrin-receptor like, and YjeF N-terminal domain

5 of 11

2.76

5.37

6.40e-11

CL:2434

Mixed, incl. Putative ephrin-receptor like, and Cysteine-type endopeptidase activity

3 of 6

2.8

2.99

3.03e-06

CL:8183

Mixed, incl. Ferric reductase transmembrane component-like domain, and Protein kinase C activity

4 of 36

2.14

2.8

2.00e-06

CL:8187

Mixed, incl. HR1 rho-binding domain, and Ferric reductase transmembrane component-like domain

3 of 12

2.5

2.57

1.47e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04145

Phagosome

3 of 68

1.74

1.22

0.0030

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1280218

Adaptive Immune System

5 of 262

1.38

1.19

0.0010

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