STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tagg_0123InterPro IPR010709; PFAM: Protein of unknown function DUF1288; SPTR: B8D4I3 Putative uncharacterized protein; PFAM: GINS complex subunit Sld5. (200 aa)    
Predicted Functional Partners:
Tagg_0122
Replicative DNA helicase Mcm; COGs: COG1241 ATPase involved in replication control Cdc46/Mcm family; InterPro IPR001208:IPR011704; KEGG: hypothetical protein; K02540 minichromosome maintenance protein 2; PFAM: MCM family protein; ATPase associated with various cellular activities AAA_5; SMART: MCM family protein; SPTR: B8D4I2 MCM family protein; PFAM: MCM2/3/5 family; Belongs to the MCM family.
     
 0.865
Tagg_0044
Hypothetical protein; SPTR: B8D6L6 Putative uncharacterized protein.
   
 
 0.827
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
     
 0.664
rfcS
Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.
     
 0.637
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.