STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tagg_0166Hypothetical protein; SPTR: B8D5H5 Putative uncharacterized protein. (116 aa)    
Predicted Functional Partners:
Tagg_0558
1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.931
Tagg_0410
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000103:IPR000815:IPR001327:IPR 004099:IPR006076:IPR006258; KEGG: scl:sce8000 pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; SPTR: B8D2P1 Dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxi [...]
  
 0.916
Tagg_1295
COGs: COG0492 Thioredoxin reductase; InterProIPR000759:IPR013027:IPR000103:IPR001327:IPR 008255; KEGG: dvl:Dvul_1324 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8D657 Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
 
 0.790
Tagg_1407
DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.752
rpl11
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
   0.721
Tagg_0167
Thermosome subunit; COGs: COG0459 Chaperonin GroEL (HSP60 family); InterProIPR017998:IPR001844:IPR002423:IPR016160:IPR 002194:IPR012714; KEGG: CCT5; chaperonin containing TCP1, subunit 5 (epsilon); K09497 T-complex protein 1 subunit epsilon; PFAM: chaperonin Cpn60/TCP-1; SPTR: B8D5H8 Thermosome subunit alpha; TIGRFAM: thermosome; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: thermosome, various subunits, archaeal.
  
 0.699
Tagg_0983
Hypothetical protein; SPTR: A3DMF5 Putative uncharacterized protein.
   
   0.631
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
   
   0.631
rps19p
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
   0.547
Tagg_0303
COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR001450:IPR012135:IPR017900:IPR005720; KEGG: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8D2W4 Dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: Dihydroorotate dehydrogenase; 4Fe-4S binding domain; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein.
  
 
 0.525
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
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