Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tagg_0232ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: tdn:Suden_2063 hypothetical protein; PFAM: ABC-3 protein; SPTR: B8D3L6 ABC-type Mn2+/Zn2+ transport system, permease component; PFAM: ABC 3 transport family. (282 aa)    
Predicted Functional Partners:
Tagg_0234
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: vvy:VV1037 zinc ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B8D3L8 ABC transporter, ATP binding protein; PFAM: ABC transporter.
 
 
 0.996
Tagg_0233
COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; KEGG: ppr:PBPRB1208 putative adhesion protein; SPTR: B8D3L7 ABC transporter, substrate binding protein; PFAM: Periplasmic solute binding protein family.
 
  
 0.987
Tagg_0231
SPTR: B8D3L5 Putative transcriptional regulator, CopG family.
     
 0.874
Tagg_0230
COGs: COG2521 methyltransferase; KEGG: xfn:XfasM23_1957 hypothetical protein; SPTR: B8D3L4 Methyltransferase-like protein; PFAM: Conserved hypothetical protein 95.
       0.812
Tagg_0495
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR000485:IPR000835:IPR001367; KEGG: dal:Dalk_2732 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; regulatory protein MarR; SMART: iron dependent repressor; SPTR: B8D4E9 Iron dependent repressor; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
  
 0.660
Tagg_0280
ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: gur:Gura_2760 cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: A3DLJ2 ABC transporter related; PFAM: ABC transporter.
    
 0.495
Tagg_0442
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593:IPR017871; KEGG: hha:Hhal_0379 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B8D2K6 ABC transporter related; PFAM: ABC transporter.
    
 0.495
Tagg_0951
Extracellular solute-binding protein family 5; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: mlo:mlr6670 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: B1L484 ABC-type dipeptide transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
 
  
 0.494
Tagg_0235
Hypothetical protein; SPTR: B8D3L9 Putative uncharacterized protein.
       0.490
Tagg_0115
ABC-2 type transporter; InterPro IPR013525:IPR000412; KEGG: har:HEAR2357 ABC-type drug export system, membrane protein; PFAM: ABC-2 type transporter; SPTR: B8D5B0 ABC-2 type transporter; PFAM: ABC-2 type transporter.
 
  
  0.486
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.