STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tagg_0448COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: dat:HRM2_14310 Aor4; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: A1S030 Aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3. (609 aa)    
Predicted Functional Partners:
Tagg_0449
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; InterPro IPR001450:IPR017900; KEGG: spc:Sputcn32_1188 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B5IVH4 4Fe-4S binding domain protein.
 
 
 
 0.964
Tagg_0105
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: dat:HRM2_38620 Aor7; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: B8D5C0 Aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
  
  
 
0.916
Tagg_0120
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: gsu:GSU0910 aldehyde:ferredoxin oxidoreductase, tungsten-containing; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: A8MCP0 Aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
  
  
 
0.916
Tagg_0058
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450:IPR017900; KEGG: dma:DMR_30980 iron-sulfur binding protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8D5G1 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain.
  
 
 0.807
Tagg_0446
Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: dde:Dde_1511 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: B8D2L2 Putative cation efflux system protein; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter.
       0.756
Tagg_0447
Hypothetical protein.
       0.752
Tagg_0619
InterPro IPR001450:IPR017900; KEGG: dat:HRM2_04900 SoxA1; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A3DKG4 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain.
   
 
 0.712
Tagg_0327
COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005111:IPR005110:IPR001453; KEGG: mes:Meso_2433 molybdenum cofactor synthesis domain-containing protein; PFAM: MoeA domain protein domain I and II; MoeA domain protein domain IV; molybdopterin binding domain; SPTR: B8D4L0 Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain.
 
   
 0.592
Tagg_0451
Protein of unknown function DUF107; COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: gur:Gura_2913 hypothetical protein; PFAM: protein of unknown function DUF107; SPTR: B8D3U2 Serine protease; PFAM: NfeD-like.
       0.556
Tagg_0450
SPFH domain, Band 7 family protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001972:IPR001107; KEGG: sfu:Sfum_0464 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: B8D3U3 Stomatin/prohibitin-like protein; PFAM: SPFH domain / Band 7 family.
       0.551
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.