Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tagg_0484Asparaginase; COGs: COG1446 Asparaginase; InterPro IPR000246; KEGG: sfr:Sfri_1445 peptidase T2, asparaginase 2; PFAM: peptidase T2 asparaginase 2; PRIAM: Beta-aspartyl-peptidase; SPTR: A3DPP6 Asparaginase; PFAM: Asparaginase. (327 aa)    
Predicted Functional Partners:
Tagg_0668
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: sfu:Sfum_3898 aminotransferase, class I and II; PFAM: aminotransferase class I and II; SPTR: B8D3W3 Aspartate aminotransferase (AspC), conjectural; PFAM: Aminotransferase class I and II.
 
  
 0.925
Tagg_0191
COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterPro IPR000310:IPR001597:IPR000192:IPR002129; KEGG: swd:Swoo_2007 pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; Orn/Lys/Arg decarboxylase major region; SPTR: B8D379 Pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain.
     
 0.827
Tagg_0483
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: nam:NAMH_0237 HAD-superfamily hydrolase subfamily IA; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: B8D438 Heavy metal translocating P-type ATPase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
       0.790
Tagg_0485
Hypothetical protein; SPTR: B8D440 Putative uncharacterized protein.
       0.621
tbp
TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
     
 0.578
Tagg_0482
COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: pin:Ping_2327 chromate transporter, chromate ion transporter (CHR) family protein; PFAM: Chromate transporter; SPTR: B8D576 Chromate transporter; PFAM: Chromate transporter.
       0.577
Tagg_0353
Sigma 54 interacting domain protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593:IPR002078:IPR017871; KEGG: hha:Hhal_0379 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B8D4P7 ABC transporter related; PFAM: ABC transporter.
  
  
 0.561
Tagg_0459
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593:IPR017871; KEGG: pca:Pcar_2396 ABC-type transport system, putative ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B8D2R9 ABC transporter related; PFAM: ABC transporter.
  
  
 0.561
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
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